We use maggots of greenbottle flies (Lucilia sericata). This is one of the most commonly used species for medical purposes throughout the world.
Mechanism of action
Step 1: Wound debridement
Maggots selectively liquefy necrotic tissue by secreting/excreting proteolytic enzymes, then ingest it by suction.
Step 2: Antimicrobial activities
Maggot secretions/excretions contain antimicrobial peptides, which are
effective against certain kinds of pathogenic bacteria, including some
kinds of anti-drug bacteria. They are also reported to degrade biofilms
of Staphylococcus aureus and Pseudomonas aeruginosa.
Step 3: Promotion of wound healing
Recent studies show that certain agents in maggot secretions/excretions also promote regrowth of healthy granulation tissue by accelerating angiogenic activity and/or fibroblast migration.